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  • Poster Presentations

    Access to the MSVirtual2020 ePosters.

    • Presentation Date(s):  Sept 11. 2020
    • Total Presentations: 1256

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  • PO01 - On-Demand ePosters P0001-P0286

    • Type: Poster
    • Presentations: 283
    Presented on: 9/11/2020, 08:00
    View Posters
    • P0001 - A new software and analysis suite for experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Biostatistical Methods

      Cole Maguire, Blaine Caslin, Sam Bazzi, Esther Melamed, Dennis Wylie

      • Poster Presentation (Video)
    • P0002 - Applying machine learning to multimodal neuroimaging data to predict visual episodic memory performance in multiple sclerosis  (View Presentation)

      Keyword: Machine Learning/Network Science

      Korhan Buyukturkoglu, Yiran Li, Ceren Tozlu, Amy Kuceyeski, James Sumowski, Victoris Leavitt

      • Poster Presentation (PDF)
    • P0003 - Combinatorial Genetic Interaction Analysis of Multiple Sclerosis Risk Variants (View Presentation)

      Keyword: Machine Learning/Network Science

      Corriene Sept, Farren Briggs

      • Poster Presentation (PDF)
    • P0004 - Convolutional neural network framework for predicting progression in early MS (View Presentation)

      Keyword: Machine Learning/Network Science

      Vinzenz Fleischer, Dumitru Ciolac, Angela Radetz, Gabriel Gonzalez-Escamilla, Julia Kroth, Julia Krämer, Sven Meuth, Sergiu Groppa, Muthuraman Muthuraman

      • Poster Presentation (PDF)
    • P0005 - Decoding the EDSS Scores of Multiple Sclerosis Patients from MRI Biomarkers (View Presentation)

      Keyword: Machine Learning/Network Science

      Roberto Paolella, Ezequiel De La Rosa, Vincenzo Anania, Stijn Denissen, Jeroen Van Schependom, Guy Nagels, Dominique Dive, Françoise Durand-Dubief, Dominique Sappey-Marinier, Dirk Smeets, Diana Sima

      • Poster Presentation (Video)
    • P0006 - Detecting treatment response on T1 gadolinium enhancing lesion burden in clinical trials of multiple sclerosis with deep learning (View Presentation)

      Keyword: Machine Learning/Network Science

      AnithaPriya Krishnan, Zhuang Song, David Clayton, Laura Gaetano, Alex De Crespigny, Thomas Bengtsson, Richard Carano

      • Poster Presentation (PDF)
    • P0007 - Detecting treatment response on T2 lesion burden in multiple sclerosis clinical trials with deep learning (View Presentation)

      Keyword: Machine Learning/Network Science

      AnithaPriya Krishnan, Zhuang Song, David Clayton, Laura Gaetano, Alex De Crespigny, Thomas Bengtsson, Richard Carano

      • Poster Presentation (PDF)
    • P0008 - Divergent patterns of ventral attention network centrality relate to cognitive conversion in MS (View Presentation)

      Keyword: Machine Learning/Network Science

      Marijn Huiskamp, Anand Eijlers, Tommy Broeders, Iris Dekker, Bernard Uitdehaag, Frederik Barkhof, Alle Meije Wink, Jeroen Geurts, Hanneke Hulst, Menno Schoonheim

      • Poster Presentation (Video)
    • P0009 - ENTIMOS: a discrete event simulation model for maximizing efficiency of infusion suites in centres treating multiple sclerosis patients (View Presentation)

      Keyword: Biostatistical Methods

      Richard Nicholas, Pamela Dobay, Kristyna Lacinova, Róisín Brennan, Marina Ziehn, Carol Lines, Nicholas Adlard

      • Poster Presentation (PDF)
    • P0010 - Integration of the Extreme Gradient Boosting model with clinical data to enable the early diagnosis of multiple sclerosis (View Presentation)

      Keyword: Machine Learning/Network Science

      Wei Qiu, Ruoning Wang, Wenjing Luo, Zifeng Liu, Weilong Liu, Chunxin Liu, Xun Liu, He Zhu, Rui Li, Jiafang Song, Xueqiang Hu, Sheng Han

      • Poster Presentation (PDF)
    • P0011 - Lesion disconnectomics using atlas-based tractography (View Presentation)

      Keyword: Machine Learning/Network Science

      Veronica Ravano, Michaela Andelova, Mario João Fartaria, Mazen Mahdi, Bénédicte Maréchal, Reto Meuli, Tomas Uher, Jan Krasensky, Manuela Vaneckova, Dana Horakova, Tobias Kober, Jonas Richiardi

      • Poster Presentation (Video)
    • P0012 - Machine-learning optimized Combinatorial MRI scale (COMRISv2) correlates highly with MS disability (View Presentation)

      Keyword: Machine Learning/Network Science

      Erin Kelly, Mihael Varosanec, Alison Wichman, Mary Sandford, Peter Kosa, Bibiana Bielekova

      • Poster Presentation (Video)
    • P0013 - Modeling a long-term virtual placebo arm for SPMS population in the EXPAND study: Comparing different statistical methods (View Presentation)

      Keyword: Biostatistical Methods

      Nicolas Rouyrre, Bruce A.C. Cree, Robert Fox, Patrick Vermersch, Gavin Giovannoni, Amit Bar-Or, Ralf Gold, Daniela Piani-Meier, Göril Karlsson, Ludwig Kappos

      • Poster Presentation (Video)
    • P0014 - Personalized and dynamic prognostic model from the Barcelona CIS cohot (View Presentation)

      Keyword: Biostatistical Methods

      Mar Tintore, Pere Carbonell-Mirabent, Susana Otero-Romero, Alvaro Cobo Calvo, Georgina Arrambide, Jordi Río, Carmen Tur, Manuel Comabella, Carlos Nos, María Jesús Arévalo-Navinés, Luciana Midaglia, Íngrid Galán, Anka Vidal-Jordana, Joaquín Castilló, Breogán Rodríguez-Acevedo, Ana Zabalza, Marta Rodríguez, Augusto Sao-Avilés, Andrea Barros, Cristina Auger, Jaume Sastre-Garriga, Alex Rovira, Xavier Montalban

      • Poster Presentation (Video)
    • P0015 - Predicted brain age as a cognitive biomarker in Multiple Sclerosis (View Presentation)

      Keyword: Machine Learning/Network Science

      Stijn Denissen, Alexander De Cock, Lars Costers, Johan Baijot, Jorne Laton, Marie D’hooghe, Miguel D'Haeseleer, Dominique Dive, Johan De Mey, Jeroen Van Schependom, Diana Sima, Guy Nagels

      • Poster Presentation (Video)
    • P0016 - Progressive multifocal leukoencephalopathy lesion and brain parenchymal segmentation from MRI using serial deep convolutional neural networks (View Presentation)

      Keyword: Machine Learning/Network Science

      Omar Al-Louzi, Snehashis Roy, Ikesinachi Osuorah, Prasanna Parvathaneni, Bryan Smith, Joan Ohayon, Pascal Sati, Dzung Pham, Steven Jacobson, Avindra Nath, Daniel Reich, Irene Cortese

      • Poster Presentation (PDF)
    • P0017 - Translating MPRAGE to MP2RAGE improves the automatic tissue and lesion segmentation in Multiple Sclerosis patients (View Presentation)

      Keyword: Machine Learning/Network Science

      Francesco La Rosa, Thomas Yu, Germán Barquero, Jean-Philippe Thiran, Cristina Granziera, Meritxell Bach Cuadra

      • Poster Presentation (PDF)
    • P0018 - Variability of the response to immunotherapy among sub-groups of patients with multiple sclerosis (View Presentation)

      Keyword: Biostatistical Methods

      Ibrahima Diouf, Charles Malpas, Dana Horakova, Eva Kubala Havrdová, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Magd Zakaria, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Sharif Hamdy, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Helmut Butzkueven, Bassem Yamout, Ayse Altintas, Vincent Van Pesch, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, R Karabudak, Federica Giuliano, Christopher McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria Sa, Ludwig Kappos, Cristina Ramo-Tello, Edgardo Cristiano, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Mark Slee, Ernest Butler, Franco Granella, Freek Verheul, Pamela McCombe, Radek Ampapa, Olga Skibina, Julie Prevost, L.G.F. Sinnige, José Luis Sánchez-Menoyo, Steve Vucic, Guy Laureys, Liesbeth Van Hijfte, Dheeraj Khurana, Richard Macdonell, Tamara Castillo-Trivino, Orla Gray, Eduardo Agüera, Ilya Kister, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Sempere, Tomas Kalincik

      • Poster Presentation (PDF)
    • P0019 - A Comparison of Digital Gait Technologies in a Population of People with MS –When the Same Isn’t Always Exactly the Same (View Presentation)

      Keyword: Biosensors

      Olivia Kaczmarek, Jared Srinivasan, Christina Burke, Ahmed Khokhar, Myassar Zarif, Barbara Bumstead, Daniel Golan, Marijean Buhse, Edward Ofori, Mark Gudesblatt

      • Poster Presentation (PDF)
    • P0020 - A down-regulation of the type I interferon signaling pathway is associated with the response to teriflunomide in multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Sunny Malhotra, Jordi Río, Juan Carlos Triviño, Anka Vidal-Jordana, Ana Zabalza, Georgina Arrambide, Breogán Rodríguez-Acevedo, Íngrid Galán, Mireia Castillo, Joaquín Castilló, Luciana Midaglia, Jaume Sastre-Garriga, Mar Tintore, Xavier Montalban, Manuel Comabella

      • Poster Presentation (Video)
    • P0021 - A propensity-matched comparison of long-term disability progression in MS patients treated with dimethyl fumarate or fingolimod (View Presentation)

      Keyword: Clinical Outcome Measures

      Robert Fox, Samantha Lancia, Gary Cutter, Ruth-Ann Marrie, Jason Mendoza, James Lewin, Amber Salter

      • Poster Presentation (Video)
    • P0022 - A systematic literature review and meta-analysis of the efficacy and effectiveness of PR-fampridine in patients with multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Trond Haider, Beate Lokke, Lea Tran, Alexandra Spidalieri, Ayo Adeyemi, Carlos Acosta, Øivind Torkildsen

      • Poster Presentation (PDF)
    • P0023 - Alemtuzumab Real World Evidence in a Private Practice Setting (View Presentation)

      Keyword: Clinical Outcome Measures

      Duy-Tan Tran, Christopher Laganke, Lee Martin, Jim Bowen, Elizabeth Poole, Nupur Greene, Risako Robinson, Avani Patel, Joanne Chia, Lobat Hashemi

      • Poster Presentation (PDF)
    • P0024 - Alemtuzumab slowed brain atrophy over 6 years in patients without relapse and MRI disease activity: post hoc analysis of the pooled CARE-MS studies (View Presentation)

      Keyword: Clinical Outcome Measures

      Lauren Glendenning, Douglas L Arnold, Maria Pia Amato, Michael Barnett, Donald Barone, David Brandes, Matthew Carraro, Giancarlo Comi, Sara Eichau, Amir Mazhari, Kunio Nakamura, Daniel Pelletier, Alex Rovira, Mar Tintore, Anthony Traboulsee, Zia Choudhry, Nadia Daizadeh, Elizabeth Poole, Heinz Wiendl

      • Poster Presentation (Video)
    • P0025 - Analysis fo the results of the establishment of a SARS-CoV-2 safety protocol for Multiple Sclerosis patients  (View Presentation)

      Keyword: Clinical Outcome Measures

      Virginia Meca-Lallana, Clara Aguirre, Carolina Díaz, Laura Cardeñoso, Angels Figuerola-Tejerina, Miguel Ruiz, Jose Vivancos

      • Poster Presentation (PDF)
    • P0026 - Analysis of association between expanded disability status scale and patient determined disease steps (View Presentation)

      Keyword: Clinical Outcome Measures

      Charles Makin, Arman Altincatal, Mark Gudesblatt, Bernd Kieseier, Carl De Moor

      • Poster Presentation (PDF)
    • P0027 - Are we ready for precision medicine in Multiple Sclerosis? A web-based survey across Europe   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      filippo Martinelli Boneschi, Sandra D'Alfonso, Alessandra Caserini, Bernhard Hemmer, Elisabeth Celius, Pablo Villoslada, An Goris, Seema Kalra, Pentti Tienari, Fredrik Piehl, Ingrid Kockum

      • Poster Presentation (PDF)
    • P0028 - Assessing the temporal relationship of serum neurofilament light and subclinical disease activity: Findings from APLIOS trial (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Amit Bar-Or, Xavier Montalban, Roman Willi, Harald Kropshofer, Petra Kukkaro, Inga Ludwig, Martin Zalesak, Krishnan Ramanathan, Dieter A. Häring, Xixi Hu, Neva Coello, Morten Bagger, Edward Fox

      • Poster Presentation (Video)
    • P0029 - Assessment of Multiple Sclerosis Severity Score and Age-Related Multiple Sclerosis Severity Score as health indicators in a population-based cohort (View Presentation)

      Keyword: Clinical Outcome Measures

      Laura Bau, Elisabet Matas, Lucía Romero-Pinel, Isabel León, Sergio Martínez-Yélamos, Antonio Martínez-Yélamos

      • Poster Presentation (PDF)
    • P0030 - Association of average blood cell telomere length with the clinical course of MS over a 10-year period (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michael Hecker, Brit Fitzner, Kathrin Jäger, Jan Bühring, Margit Schwartz, Michael Walter, Uwe Zettl

      • Poster Presentation (PDF)
    • P0031 - Asymptomatic anterior optic pathway involvement in early multiple sclerosis and clinically isolated syndromes (View Presentation)

      Keyword: Clinical Outcome Measures

      Marco Pisa, Tommaso Croese, Gloria Dalla Costa, Simone Guerrieri, Su-Chun Huang, Lorena Fabbella, Annamaria Finardi, Bruno Colombo, Francesca Sangalli, Lucia Moiola, Vittorio Martinelli, Giancarlo Comi, Roberto Furlan, Letizia Leocani

      • Poster Presentation (PDF)
    • P0032 - Baseline serum Neurofilament light chain levels predict conversion to McDonald 2005 MS within 2 yrs of a first clinical demyelinating event in REFLEX (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      James Plested, Jens Kuhle, David Leppert, Giancarlo Comi, Nicola De Stefano, Ludwig Kappos, Mark Freedman, Delphine Issard, Sanjeev Roy

      • Poster Presentation (Video)
    • P0033 - Baseline serum neurofilament light levels have prognostic value for on-study MRI activity: Results from ASCLEPIOS trials (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Jens Kuhle, Ludwig Kappos, Anne H. Cross, Roman Willi, Bingbing Li, Petra Kukkaro, Harald Kropshofer, Dieter A. Häring, Krishnan Ramanathan, Martin Merschhemke, Stephen Hauser

      • Poster Presentation (Video)
    • P0034 - Can Digital Biomarkers Acquired on a Smarphone Distinguish Healthy Controls from Radiologically Isolated Syndrome Subjects? (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Mikael Cohen, Salim Fakir, Lydiane Mondot, Cassandre Landes, Christine Lebrun-Frenay

      • Poster Presentation (PDF)
    • P0035 - Can gait modelling predict disease progression in MS? A study using small body worn sensors in a clincial setting.  (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      David Paling, Lorenza Angelini, Ellen Buckley, Tecla Bonci, Alex Radford, Basil Sharrack, Siva Nair, Claudia Mazza

      • Poster Presentation (Video)
    • P0036 - Cerebral hypometabolism is a marker of disease severity in multiple sclerosis: a non-invasive imaging study using T2-Relaxation-Under-Spin-Tagging MRI (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Olwen Murphy, Zixuan Lin, Grigorios Kalaitzidis, Eleni Vasileiou, Angeliki Filippatou, Kathryn Fitzgerald, Henrik Ehrhardt, Jeffrey Lambe, Elias Sotirchos, Blake Dewey, Yihao Liu, Jerry Prince, Peter Calabresi, Hanzhang Lu, Shiv Saidha

      • Poster Presentation (PDF)
    • P0037 - Change in serum neurofilament light chain levels: ENSEMBLE 1-year interim results (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Kiran Tailor, Robert Bermel, Thomas Berger, Bruno Brochet, Mark Freedman, Trygve Holmøy, Joep Killestein, Francesco Patti, Amy Perrin Ross, Timothy Vollmer, J Beltra, Regine Buffels, T Kuenzel, Hans Peter Hartung

      • Poster Presentation (Video)
    • P0038 - CHIT1 at Diagnosis Reflects Long-Term Multiple Sclerosis Disease Activity (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Emanuela Oldoni, Ide Smets, Klara Mallants, Marijne Vandebergh, Lies Van Horebeek, Koen Poesen, Patrick Dupont, Bénédicte Dubois, An Goris

      • Poster Presentation (Video)
      • Poster Presentation (PDF)
    • P0039 - Circulating microRNAs as potential inflammatory biomarkers of acute exacerbation in relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tatiana Koudriavtseva, Annunziata Stefanile, Sara Donzelli, Giovanni Blandino, Andrea Sacconi, Laura Conti, Svetlana Lorenzano, Silvana Zannino, Fulvia Pimpinelli, Giovanna D'Agosto, Enea Gino Di Domenico, Marta Maschio, Marco Salvetti, Matilde Inglese

      • Poster Presentation (PDF)
    • P0040 - Cladribine tablets versus other DMT in achieving disability improvement in relapsing remitting multiple sclerosis patients – network meta-analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Karolina Piasecka-Stryczynska, Miroslaw Rolka, Lukasz Kaczynski, Magdalena Gorecka, Rafal Wojcik, Iwona Adamek, Marcin Kaczor, Konrad Rejdak

      • Poster Presentation (PDF)
    • P0041 - Clinical characteristics and outcome of late onset Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Ellen Iacobaeus, Anders Berglund, Kyla McKay, Lou Brundin, Jan Hillert

      • Poster Presentation (PDF)
    • P0042 - Clinical evolution of spasticity in adults with multiple sclerosis: systematic review (View Presentation)

      Keyword: Clinical Outcome Measures

      Tracey Jones-Hughes, Carlos Vila Silván, Joanna Campbell, Daniela Ortin Sulbaran, Richard Stork, Louise Crathorne

      • Poster Presentation (PDF)
    • P0043 - Clinical practice experience with Cladribine in Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Virginia Meca-Lallana, Clara Aguirre, Javier Torres, Carolina Díaz, Beatriz Del Río, Rosalía Martín, Jose Vivancos

      • Poster Presentation (PDF)
    • P0044 - CogEval in the Real World: Feasibility, Implementation, and Real World Implications (View Presentation)

      Keyword: Clinical Outcome Measures

      John Kramer

      • Poster Presentation (PDF)
    • P0045 - Comorbidities present before the MS diagnosis are not predictors for progression (View Presentation)

      Keyword: Clinical Outcome Measures

      Marco De Caneda, Camila Batista, MARIA CECÍLIA De Vecino

      • Poster Presentation (PDF)
    • P0046 - Comparative Effectiveness of Ozanimod Versus Dimethyl Fumarate: Results of a Matching-Adjusted Indirect Comparison (View Presentation)

      Keyword: Clinical Outcome Measures

      Jenna Zeringo, Stanley Cohan, Jinender Kumar, Stella Arndorfer, Xuelian Zhu, Marko Zivkovic, Tom Tencer

      • Poster Presentation (PDF)
    • P0047 - Comparative Efficacy and Safety of Ozanimod Versus Teriflunomide for Relapsing-Remitting Multiple Sclerosis: a Matching-Adjusted Indirect Comparison (View Presentation)

      Keyword: Clinical Outcome Measures

      Jenna Zeringo, Stanley Cohan, Jinender Kumar, Stella Arndorfer, Xuelian Zhu, Marko Zivkovic, Tom Tencer

      • Poster Presentation (PDF)
    • P0048 - Comparative Efficacy of Relapsing Multiple Sclerosis Therapies: A Longitudinal Model-Based Meta-Analysis for Confirmed Disability Accumulation (View Presentation)

      Keyword: Clinical Outcome Measures

      Matthew Zierhut, Hilke Kracker, Tatiana Scherz, Alexander Keenan, Brian Hennessy

      • Poster Presentation (PDF)
    • P0049 - Comparative Efficacy of Relapsing Multiple Sclerosis Therapies: A Model-Based Meta-Analysis for Annual Relapse Rate (View Presentation)

      Keyword: Clinical Outcome Measures

      Matthew Zierhut, Hilke Kracker, Tatiana Scherz, Alexander Keenan, Brian Hennessy

      • Poster Presentation (PDF)
    • P0050 - Comparative transcriptomics of multiple sclerosis vs. viral infections, including SARS-CoV-2 (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      George Vavougios, Marianthi Breza, Theodoros Mavridis, Sotirios Zarogiannis, Karen Krogfelt, Erietta Sygkliti Pelidou, Triantafyllos Doskas

      • Poster Presentation (PDF)
    • P0051 - Comparison of serum and CSF fluid biomarkers for predicting long term disease progression in MS   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Simon Thebault, Mohammad Abdoli, Seyed Mohammad Fereshtehnejad, Daniel Tessier, Vincent Tabard-Cossa, Mark Freedman

      • Poster Presentation (PDF)
    • P0052 - Completion rates by clinicians in global MS studies for the electronic EDSS compared to paper (View Presentation)

      Keyword: Clinical Outcome Measures

      Jenny Ly, Rinah Yamamoto

      • Poster Presentation (PDF)
    • P0053 - Correlation Between Spinal Fluid and Blood Levels of Neurofilament Light, GFAP, Tau, and UCHL1: Do We Need a Correction Factor? (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Enrique Alvarez, Alanna Ritchie, Kavita Nair, Robert Gross, Amanda Piquet, Courtney Knapp, Sean Selva, Stefan Sillau, Jeffrey Bennett, Greg Owens, Timothy Vollmer

      • Poster Presentation (PDF)
    • P0054 - Cost of a relapse-free patient in relapsing-remitting multiple sclerosis, a reliable result-based health indicator. (View Presentation)

      Keyword: Clinical Outcome Measures

      Lucía Romero-Pinel, Laura Bau, Elisabet Matas, Isabel León, Roser Juvany, Ramon Jódar, Antonio Martínez-Yélamos, Sergio Martínez-Yélamos

      • Poster Presentation (PDF)
    • P0055 - Cross-sectional and longitudinal estimation of radiographic and clinical endpoints to quantify MS disease trajectory with blood serum protein levels. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Jens Kuhle, David Leppert, Pascal Benkert, Johanna Oechtering, Annette Orleth, Özgür Yaldizli, Michael Becich, Victor Gehman, Amal Katrib, Fatima Rubio Da Costa, Ferhan Qureshi, Cristina Granziera

      • Poster Presentation (PDF)
    • P0056 - CSF inflammatory profile of primary progressive multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Damiano Marastoni, Stefania Rossi, Anna Bolzan, Anna Pisani, Valentina Mazziotti, Marco Castellaro, Roberta Magliozzi, Salvatore Monaco, Massimiliano Calabrese

      • Poster Presentation (PDF)
    • P0057 - Decline in serum neurofilament is associated with decreased clinical and radiological disease activity over two years of dimethyl fumarate treatment (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Katja Akgün, Monique Schreiner, Justin Bohn, Kathryn Fitzgerald, Jordan Messer, Ellen Mowry, Elias Sotirchos, Peter Calabresi, Bernd Kieseier, Tjalf Ziemssen

      • Poster Presentation (PDF)
    • P0058 - Decrease of peripheral CD19+ IgG+ B-cells with age and immunotherapy in patients with relapsing remitting Multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tobias Keiner, Alexander Hapfelmeier, Bernhard Hemmer

      • Poster Presentation (PDF)
    • P0059 - Defining predictors of disease activity and worsening in multiple sclerosis: an analysis of the CombiRx trial (View Presentation)

      Keyword: Clinical Outcome Measures

      Yinan Zhang, Stacey Cofield, Gary Cutter, Stephen Krieger, Jerry Wolinsky, Fred Lublin

      • Poster Presentation (PDF)
    • P0060 - Descriptive study on recruitment effort for a remote monitoring study in Multiple Sclerosis: RADAR study (View Presentation)

      Keyword: Clinical Outcome Measures

      Ana Zabalza, Ana Isabel Guerrero, M Buron, Gloria Dalla Costa, M. L. La Porta, M. Martinis, Melinda Magyari, J. Melchert, L. Rosselli, Carlos Nos, Letizia Leocani, Per S. Sorensen, Xavier Montalban, Bernd Kieseier, Giancarlo Comi

      • Poster Presentation (PDF)
    • P0061 - Determining the effect of blood anticoagulants on the detection level of neurobiomarkers in headache and control patients on the SIMOA platform (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Alanna Ritchie, Sean Selva, Greg Owens, Courtney Knapp, Jose Parra Gonzalez, Enrique Alvarez, Kavita Nair, Timothy Vollmer

      • Poster Presentation (PDF)
    • P0062 - Developing standard data of cognitive function using Processing Speed Test in Japanese healthy volunteers and comparison to the US normative data (View Presentation)

      Keyword: Clinical Outcome Measures

      Masaaki Niino, Yusei Miyazaki, Michihiro Kanda, Michael Edwards, Carl De Moor, Arman Altincatal, James R. Williams, Bernd Kieseier, Stephen Rao

      • Poster Presentation (PDF)
    • P0063 - Development of a Custom Multivariate Proteomic Serum Based Assay for Association with Radiographic and Clinical Endpoints in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tanuja Chitnis, Michael Becich, Riley Bove, Bruce Cree, Victor Gehman, Refugia Gomez, Stephen Hauser, Roland Henry, Amal Katrib, Hrishikesh Lokhande, Jorge Oksenberg, Anu Paul, Ferhan Qureshi, Adam Santaniello, Neda Sattarnezhad, Shrishti Saxena, Howard Weiner, Michael Wilson, Hajime Yano, Sergio Baranzini

      • Poster Presentation (Video)
    • P0064 - Development of the international, multidisciplinary, patient-relevant standard outcome set for Multiple Sclerosis: the S.O.S.MS project (View Presentation)

      Keyword: Clinical Outcome Measures

      Kirsten Daniels

      • Poster Presentation (PDF)
    • P0065 - Differential neuroinflammation genes expression in benign and highly active multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Maria Ivanova, Anastasya Voronkova, Maria Zakharova

      • Poster Presentation (PDF)
    • P0066 - Dimethyl fumarate decreases serum neurofilament light chain in relapsing-remitting multiple sclerosis patients. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Susana Sainz de la Maza, Paulette Esperanza Walo Delgado, Noelia Villarrubia, Enric Monreal, Mercedes Espiño, Jose Ignacio Fernandez-Velasco, Jaime Masjuan, Lucienne Costa-Frossard, Luisa María Villar

      • Poster Presentation (PDF)
    • P0067 - Disability improvement by Multiple Sclerosis Functional Composite in progressive MS patients and MRI features (View Presentation)

      Keyword: Clinical Outcome Measures

      Tanuja Chitnis, Matthew McAdams, Mark Anderson, Mariann Polgar-Turcsanyi, Mattia Rosso, Bonnie Glanz, Taylor Saraceno, Ralph Kern, Susan Ward, Munish Mehra, Howard Weiner, Brian Healy

      • Poster Presentation (PDF)
    • P0068 - Disability Progression in MS Participants Treated with Delayed-release Dimethyl Fumarate: Age-related Subgroup Analysis of the NARCOMS Registry (View Presentation)

      Keyword: Clinical Outcome Measures

      Amber Salter, Samantha Lancia, Gary Cutter, Robert Fox, Ruth-Ann Marrie, Jason Mendoza, James Lewin

      • Poster Presentation (Video)
    • P0069 - dreams: developing a comprehensive, sensitive and validated set of digital biomarkers for MS (View Presentation)

      Keyword: Biosensors

      Yvonne Naegelin, Johannes Lorscheider, Tim Woelfle, Silvan Pless, Jens Kuhle, Oscar Reyes, Andrea Wiencierz, Ludwig Kappos

      • Poster Presentation (PDF)
    • P0070 - Effect of evobrutinib, a BTK inhibitor, on immune cell and immunoglobulin levels in relapsing MS: an open-label extension to a phase II study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Xavier Montalban, Jamie Shaw, Fernando Dangond, Emily Martin, Roland Grenningloh, Martin Weber, Ying Li

      • Poster Presentation (Video)
    • P0071 - Effect of oral ponesimod on clinical disease activity and MRI-based outcomes in patients with relapsing multiple sclerosis: Phase 3 OPTIMUM study (View Presentation)

      Keyword: Clinical Outcome Measures

      Priya Ganpathy, Ludwig Kappos, Michel Burcklen, Mark Freedman, Robert Fox, Eva Kubala Havrdová, Brian Hennessy, Reinhard Hohlfeld, Fred Lublin, Xavier Montalban, Carlo Pozzilli, Tatiana Scherz, Philippe Linscheid, Magdalena Pirozek-Lawniczek, Lisa Ford, Hilke Kracker, Jens Wuerfel, Till Sprenger

      • Poster Presentation (PDF)
    • P0072 - Effect of switching disease modifying drugs on relapse rate in stable relapsing remitting multiple sclerosis patients planning for pregnancy. (View Presentation)

      Keyword: Clinical Outcome Measures

      Lubna Almouzain, Fiona Hamilton, Fiona Stevenson, Declan Chard, Nur Abdulrahman

      • Poster Presentation (PDF)
    • P0073 - Effectiveness of peginterferon beta-1a versus non-pegylated interferons and glatiramer acetate in a real-world setting using propensity score matching (View Presentation)

      Keyword: Clinical Outcome Measures

      Stefan Braune, Arnfin Bergmann, Fabian Roßnagel, Kirsi Taipale, Fabio Pellegrini, Thijs Koster, Karin Rehberg-Weber

      • Poster Presentation (PDF)
    • P0074 - Effects of Ocrelizumab on Cognition-Real World Evidence Using the CogEval App (View Presentation)

      Keyword: Clinical Outcome Measures

      John Kramer

      • Poster Presentation (PDF)
    • P0075 - Efficacy of Rituximab in Adult and Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Systematic Review and Meta-analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Smathorn Thakolwiboon, Jie Pan, Amputch Karukote, Hannah Zhao-Fleming, Mirla Avila

      • Poster Presentation (Video)
    • P0076 - Evaluation of diagnosis and treatment practices in patients with Multiple Sclerosis by Brazilian neurologists’ experts in demyelinating disorders. (View Presentation)

      Keyword: Clinical Outcome Measures

      Cássia Elisa Marin, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Óscar Fernández, Antônio Pereira Gomes Neto, Cláudia Cristina Ferreira Vasconcelos, José Artur Costa D’almeida, Marcus Vinícius Magno Gonçalves, Maria Fernanda Mendes, Mônica Koncke Fiuza Parolin, Osvaldo Nascimento, Paulo Diniz Gama, Rafael Paternó Castello Dias-Carneiro, Ronaldo Maciel Dias, Alfredo Damasceno, Jefferson Becker

      • Poster Presentation (Video)
    • P0077 - Evaluation of Quality of Life and Fatigue in Patients Followed in Multiple Sclerosis Outpatient Clinic (View Presentation)

      Keyword: Clinical Outcome Measures

      Gençer Genç, Ülgen Yalaz Tekan, Esin Ayşe Özbek, Nazan Konakçı, Serpil Bulut

      • Poster Presentation (PDF)
    • P0078 - Evidence for the efficacy of nabiximols oromucosal spray in the management of patients with spasticity: A systematic review (View Presentation)

      Keyword: Clinical Outcome Measures

      Louise Crathorne, Joanna Campbell, Carlos Vila Silván, Richard Stork, Daniela Ortin Sulbaran

      • Poster Presentation (PDF)
    • P0079 - Experience in Multiple Sclerosis Patients with SARS CoV-2 Infection (View Presentation)

      Keyword: Clinical Outcome Measures

      Virginia Meca-Lallana, Clara Aguirre, Carolina Díaz, Beatriz Del Río, Rosalía Martín, Jose Vivancos

      • Poster Presentation (PDF)
    • P0080 - Exploring neurofilament light in CSF as a biomarker for multiple sclerosis in clinical practice (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Igal Rosenstein, Lenka Novakova, Markus Axelsson, Kaj Blennow, Henrik Zetterberg, Jan Lycke

      • Poster Presentation (PDF)
    • P0081 - Exploring the usability and patient satisfaction of a virtual rehabilitation program in multiple sclerosis: The RehabVR study protocol (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Daniel Prefasi , Virginia Meca-Lallana, Walter Alabarcez, Teresa Hernandez, Fabiola Garcia, Angelica Portaña, David Gomis, Nieves Tellez, Cristina Garcia-Bernaldez, Jorge Mauriño, Nicolas Medrano, Aranzazu Vazquez

      • Poster Presentation (PDF)
    • P0082 - From proteome to interactome: a mechanistic approach to MS biomarker discovery (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Amal Katrib, Ferhan Qureshi, Michael Becich, Victor Gehman, Susan Goelz

      • Poster Presentation (PDF)
    • P0083 - Gadolinium improves detection of central vein lesions in MS using 3T FLAIR*. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Lynn Daboul, Carly O'Donnell, David Moreno-Dominguez, Paulo Rodrigues, John Derbyshire, Christina Azevedo, Amit Bar-Or, Eduardo Caverzasi, Peter Calabresi, Bruce Cree, Leorah Freeman, Roland Henry, Erin Longbrake, Jiwon Oh, Nico Papinutto, Daniel Pelletier, Rohini Samudralwar, Matthew Schindler, Elias Sotirchos, Nancy Sicotte, Andrew Solomon, Russell Shinohara, Daniel Reich, Pascal Sati, Daniel Ontaneda

      • Poster Presentation (PDF)
    • P0084 - Gene expression profiling and TCR diversity of ATA188, an off-the-shelf, allogeneic EBV-targeted T-cell immunotherapy for progressive MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Claire Jones, P Foubert, S Srihari, L Le Texier, R R Shen, F Forozan, C Smith, R Khanna, B T Aftab

      • Poster Presentation (PDF)
    • P0085 - Harmonization of real-world studies in multiple sclerosis: retrospective analysis from the RIReMS group (View Presentation)

      Keyword: Clinical Outcome Measures

      Marcello Moccia, Pietro Annovazzi, Maria Chiarav Buscarinu, Massimiliano Calabrese, Paola Cavalla, Cinzia Cordioli, Massimiliano Di Filippo, Diana Ferraro, Alberto Gajofatto, Antonio Gallo, Roberta Lanzillo, Alice Laroni, Loredana Lorefice, Simona Malucchi, Viviana Nociti, Damiano Paolicelli, Federica Pinardi, Luca Prosperini, Marta Radaelli, Paolo Ragonese, Valentina Tomassini, Carla Tortorella, Eleonora Cocco, Claudio Gasperini, Claudio Solaro

      • Poster Presentation (PDF)
    • P0086 - Highly sensitive quantitation of CXCL13 as an intrathecal biomarker in optic neuritis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Mads Nikolaj Olesen, Anna Christine Nilsson, Gorm Pihl-Jensen, Kerstin Kathrine Soelberg, Dorte Aalund Olsen, Ivan Brandslund, Søren Thue Lillevang, Jonna Skov Madsen, Jette Lautrup Frederiksen, Nasrin Asgari

      • Poster Presentation (PDF)
    • P0087 - Identification of proteins associated with ageing in patients with progressive multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Nicolás Fissolo, Luciana Midaglia, Begoña Oliver, Luisa María Villar, Antonio José Sánchez-López, Albert Saiz, Roberto Alvarez-Lafuente, Lluís Ramió I Torrentà, Sergio Martínez-Yélamos, Xavier Montalban, Manuel Comabella

      • Poster Presentation (PDF)
    • P0088 - Identification of putative multiple sclerosis biomarkers in CSF by targeted-mass spectrometry (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Dorsa Sohaei, Simon Thebault, Ihor Batruch, Ioannis Prassas, Mark Freedman, Eleftherios Diamandis

      • Poster Presentation (Video)
    • P0089 - IFP35 as biomolecular marker of neuroinflammation and treatment response in Multiple Sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Roberto De Masi, Stefania Orlando

      • Poster Presentation (PDF)
    • P0090 - Immune cell profiles associated with CIS progression and stability using RNA-seq single-cell analysis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      James Giarraputo, Vaibhav Jain, Stephanie Arvai, Dawn Smilek, Kristina Harris, Simon Gregory

      • Poster Presentation (Video)
    • P0091 - Improving patient outcomes through a comprehensive care management platform (MOVING MS) (View Presentation)

      Keyword: Clinical Outcome Measures

      Annalise Miner, Michael Becich, Victor Gehman, Jennifer Graves

      • Poster Presentation (Video)
    • P0092 - Incidence of recurrence of disease activity after fingolimod discontinuation in older patients (View Presentation)

      Keyword: Clinical Outcome Measures

      Vasiliki Pantazou, Caroline Pot, Geraldine Le Goff, Renaud Du Pasquier, Marie Theaudin

      • Poster Presentation (PDF)
    • P0093 - Increased serum GFAP associates with microstructural white matter damage in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Maija Saraste, Svetlana Bezukladova, Markus Matilainen, Marcus Sucksdorff, Jens Kuhle, David Leppert, Laura Airas

      • Poster Presentation (PDF)
    • P0094 - Inter-laboratory evaluation of cerebrospinal fluid and serum kappa free light chain measurements (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Diana Ferraro, Roberta Bedin, Patrizia Natali, Diego Franciotta, Gaetano Bernardi, Elena Corsini, Eleonora Cocco, Gianna Costa, Ilaria Crespi, Marta Lamonaca, Arianna Sala, Cinzia Nicolò, Massimiliano Di Filippo, Alfredo Villa, Viviana Nociti, Teresa De Michele, Paola Cavalla, Paola Caropreso, Francesca Vitetta, Matteo Gastaldi, Tommaso Trenti, Stefano Meletti, Patrizia Sola

      • Poster Presentation (PDF)
    • P0095 - Intracortical motor conduction is associated with dexterity in progressive multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Marco Pisa, Raffaella Chieffo, Martina Congiu, Federica Esposito, Marzia Romeo, Mauro Comola, Giancarlo Comi, Letizia Leocani

      • Poster Presentation (PDF)
    • P0096 - Intrathecal immunoglobulin M synthesis is associated with higher disease activity and severity in Multiple Sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johanna Oechtering, Sabine Schaedelin, Pascal Benkert, Stefanie Müller, Lutz Achtnichts, Jochen Vehoff, Giulio Disanto, Oliver Findling, Bettina Fischer-Barnicol, Annette Orleth, Andrew Chan, Anke Salmen, Caroline Pot, Cristina Granziera, Ingmar Heijnen, Patrice Lalive, Jens Wuerfel, Therese Lincke, Johanna Lieb, Özgür Yaldizli, Tim Sinnecker, Tobias Derfuss, Axel Regeniter, Chiara Zecca, Claudio Gobbi, Ludwig Kappos, David Leppert, Jens Kuhle

      • Poster Presentation (PDF)
    • P0097 - Intrathecal immunoglobulin M synthesis is associated with higher serum neurofilament light chain levels and increased MRI disease activity in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johanna Oechtering, Sabine Schaedelin, Pascal Benkert, Muhamed Barakovic, Aleksandra Maceski, Annette Orleth, Dimitri Rey, Tim Sinnecker, Reza Rahmanzadeh, Sabrina Zadic, Riccardo Galbusera, Ramona-Alexandra Todea, Alessandro Cagol, Lutz Achtnichts, Stefanie Aeschbacher, Klaus Berger, Andrew Chan, David Conen, Tobias Derfuss, Giulio Disanto, Oliver Findling, Bettina Fischer-Barnicol, Ingmar Heijnen, Kevin Hrusovsky, Harald Kropshofer, Patrice Lalive, Johanna Lieb, Therese Lincke, Johannes Lorscheider, Pietro Maggi, Christian Müller, Stefanie Müller, Yvonne Naegelin, Jorge Oksenberg, Caroline Pot, Renaud Du Pasquier, Ernst-Wilhelm Radue, Axel Regeniter, Anke Salmen, Jochen Vehoff, Emmanuelle Waubant, Sven Wellmann, Heinz Wiendl, Jens Würfel, Özgür Yaldizli, Chiara Zecca, David Leppert, Claudio Gobbi, Ludwig Kappos, Cristina Granziera, Jens Kuhle

      • Poster Presentation (PDF)
    • P0098 - Investigation of biomarkers in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Burak Arslan, Gökçe Arslan, Aylin Dinçel, R Karabudak, Aslı Tuncer

      • Poster Presentation (PDF)
    • P0099 - Is disease activity prior to fingolimod initiation in treatment-naive patients predictive of response?  (View Presentation)

      Keyword: Clinical Outcome Measures

      Vasiliki Pantazou, Renaud Du Pasquier, Geraldine Le Goff, Caroline Pot, Marie Theaudin

      • Poster Presentation (PDF)
    • P0100 - Italian prospective multicentric observational real-life study of aggressive Relapsing Remitting Multiple Sclerosis treated with alemtuzumab (View Presentation)

      Keyword: Clinical Outcome Measures

      Lucia Moiola, Maria Di Cristinzi, Andrea Sultana, Chiara Zanetta, Francesca Rinaldi, LAURA Brambilla, Jessica Frau, Simona Malucchi, Pietro Annovazzi, giorgia Puorro, Assunta Bianco, Giacomo Lus, Paola Cavalla, Francesca Sangalli, Marzia Romeo, Gerola Marfia, Antonio Gallo, Valeria Barcella, Sebastiano Bucello, Maria Teresa Ferrò, caterina Lapucci, Luca Chiveri, Clara Grazia Chisari, Eleonora Baldi, Raffaella Clerici, Paola Banfi, carla Tortorella, Rocco Totaro, Raffaella Cerqua, Simone Tonietti, Vittorio Mantero, Giuseppe Santuccio, Massimo Filippi

      • Poster Presentation (PDF)
    • P0101 - Kinematic assessment of upper limb function in progressive multiple sclerosis (View Presentation)

      Keyword: Biosensors

      Linford Fernandes, Awais Hafeez, Rachel Coats, Mark Mon-Williams, Helen Ford

      • Poster Presentation (PDF)
    • P0102 - KonectomTM smartphone-based digital outcome assessment of cognitive and motor function in multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Christine Guo, Ellen Cahir-Mcfarland, Julien Dumail, Thibaud Guymard, Jenna McLoughlin, Séverine Bieuvelet, Morgane Vallée, Saad Zinaï, Vanessa Beynon, Matt Scaramozza, Nathalie Franchimont, Shibeshih Belachew

      • Poster Presentation (PDF)
    • P0103 - Liothyronine treatment of MS patients alters proteins in CSF related to angiogenesis and immune function (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Pavan Bhargava, Thomas Shoemaker, Sarah Snoops, Sandra Cassard, Fan Tian, Kathryn Fitzgerald, David Cooper, Jenna Mammen, Ellen Mowry, Peter Calabresi, Scott Newsome

      • Poster Presentation (PDF)
    • P0104 - Long term disability trajectories in multiple sclerosis: a group-based trajectory analysis of the AusLong cohort (View Presentation)

      Keyword: Clinical Outcome Measures

      Mohammad Hussain, Ingrid Van Der Mei, Robyn Lucas, Anne-Louise Ponsonby, Bruce Taylor

      • Poster Presentation (PDF)
    • P0105 - Longitudinal proteomic analysis of MS patients before and after autologous hematopoietic stem cell transplantation (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Simon Thebault, Seyed Mohammad Fereshtehnejad, Veronique Laforte, Mark Freedman, David Juncker, Amit Bar-Or

      • Poster Presentation (PDF)
    • P0106 - Long-term single-centre experience with natalizumab. (View Presentation)

      Keyword: Clinical Outcome Measures

      Pierre Duquette, Pierre-Olivier Despault, Elaine Roger, Alexandre Prat, Catherine Larochelle, Marc Girard

      • Poster Presentation (PDF)
    • P0107 - Lymphocyte response in standard and extended interval dosing of natalizumab (View Presentation)

      Keyword: Clinical Outcome Measures

      Shameer Rafee, Laura Kennelly, Chris McGuigan

      • Poster Presentation (PDF)
    • P0108 - Meta-analysis of randomized controlled trials and real-world evidence comparing natalizumab and fingolimod for relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Christina Eavis, Orestis Efthimiou, Carlos Acosta, Patrick Saunders-Hastings, Fabio Pellegrini

      • Poster Presentation (PDF)
    • P0109 - microRNA expression and its association with disability and brain atrophy (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Carlos Lopez De Silanes, Yolanda Aladro Benito, Laura De Torres, Ignacio Casanova, Sara Abellán Ayuso, Silvia Pérez-Pérez, María Ángel García-Martínez, Miriam Eimil Ortiz, Beatriz Oyanguren Rodeño, María José Gil Moreno, Rodrigo Terrero Carpio, Miguel Ángel Saiz Sepúlveda, Blanca Patricia Diaz Montoya, Esther De Antonio Sanz, Marta González Salaices, María Inmaculada Domínguez-Mozo, Roberto Alvarez-Lafuente

      • Poster Presentation (PDF)
    • P0110 - Modulation of cerebrospinal fluid immunoglobulins by ocrelizumab treatment (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michelle Gheen, Martin Weber, H.-Christian Von Büdingen, Amit Bar-Or, Ann Herman, Chris Harp, Jinglan Pei, Ryan Winger, Jeffrey Bennett, Robert Carruthers, Keith Edwards, Robert Fallis, Jeffrey Gelfand, Paul Giacomini, Benjamin Greenberg, David A. Hafler, Erin Longbrake, Carolina Ionete, Ulrike W Kaunzner, Christopher Lock, Gabriel Pardo, Fredrik Piehl, Tjalf Ziemssen, Anne H. Cross

      • Poster Presentation (Video)
    • P0111 - Monitoring Multiple Sclerosis Treatment with Plasma Biomarkers: NfL, GFAP, UCH-L1, and Tau (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Robert Gross, Alanna Ritchie, Sean Selva, Jose Parra Gonzalez, Courtney Knapp, Stefan Sillau, Greg Owens, Kavita Nair, Timothy Vollmer, Enrique Alvarez

      • Poster Presentation (PDF)
    • P0113 - MRI activity as a predictor of suboptimal response to natalizumab treatment: single center prospective cohort trial (View Presentation)

      Keyword: Clinical Outcome Measures

      Dmitry Kasatkin, Nikolay Spirin, Natalya Spirina, Ekaterina Kiseleva, Svetlana Molchanova

      • Poster Presentation (PDF)
    • P0114 - MS Biomarker Discovery: a multi-modal approach to identify biomarkers of myelin repair by leveraging a preclinical rodent model of MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Yea Jin Kaeser-Woo, Elena Morozova, Peter Cheng-te Chou, Wanyong Zeng, Bin Wang, Jessica Dion, Brian Harvey, David Koske, Dan Ferretti, Hui-Hsin Tsai, Daniel P. Bradley, Kirsten Sigrist, Raja Sriperumbudur, Tzu-Ying Liu, Wenting Wang

      • Poster Presentation (PDF)
    • P0115 - mSteps: A pilot study using a phone application with GPS, accelerometers and Wi-Fi positioning to measure walking distance in MS, indoors and outdoors (View Presentation)

      Keyword: Clinical Outcome Measures

      Sarah Alexander, Marie Braisher, Carmen Tur, Jeremy Chataway

      • Poster Presentation (PDF)
    • P0116 - Multiple Sclerosis and Cognitive Impairment: Computerized Cognitive Assessment and PROMIS-Cognitive Function Questionnaire: An Unfulfilled Promis (View Presentation)

      Keyword: Clinical Outcome Measures

      Olivia Kaczmarek, Jared Srinivasan, Myassar Zarif, Barbara Bumstead, Marijean Buhse, Daniel Golan, Jeffery Wilken, kaitlyn Jaenicke, Wendy Doroski, Deborah Lund, Mark Gudesblatt

      • Poster Presentation (PDF)
    • P0117 - Mystery of MRZ reaction in multiple sclerosis   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Samuel Wachamo, RUTURAJ Masvekar, Peter Kosa, Mihael Varosanec, Bibiana Bielekova

      • Poster Presentation (PDF)
    • P0118 - Neurofilament light chain concentration predicts risk of relapse in participants with relapsing multiple sclerosis in phase 3 ozanimod trials (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johanna Moore, Sarah Harris, Giancarlo Comi, Bruce Cree, Douglas L Arnold, Lawrence Steinman, James Sheffield, Harry Southworth, Ludwig Kappos, Jeffrey Cohen

      • Poster Presentation (PDF)
    • P0119 - Neurofilament light chain levels correlate with lesion activity and axonal damage in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Aletta Van Den Bosch, Nina Fransen, Matthew Mason, Annemieker Rozemuller, Charlotte Teunissen, Joost Smolders, Inge Huitinga

      • Poster Presentation (Video)
    • P0120 - Neuroperformance test outcomes as predictors of employment in a large, heterogeneous real world MS populations: Results from MS PATHS (View Presentation)

      Keyword: Clinical Outcome Measures

      Carl De Moor, James Williams, Lauren Krupp, Marisa McGinley, Kathryn Fitzgerald, Stephen Rao, Richard Rudick

      • Poster Presentation (PDF)
    • P0121 - Objective measurement of speech correlates with disease status and quality of life in people with MS without dysarthria (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gustavo Noffs, Frederique Boonstra, Thushara Perera, Helmut Butzkueven, Scott Kolbe, Fernanda Maldonado, Eduardo Lizama, Mary Galea, Jim Stankovich, Andrew Evans, Adam Vogel, Anneke Van Der Walt

      • Poster Presentation (PDF)
    • P0122 - Ocrelizumab in patients with multiple sclerosis: A single center experience.  (View Presentation)

      Keyword: Clinical Outcome Measures

      Chad Brady, Dhairya Lakhani, Bob Hou, Jeffery Carpenter, Weidong Luo, Sebastian Magda, Robert Haxton, Richa Tripathi, Gerard Deib, Shitiz Sriwastava

      • Poster Presentation (PDF)
    • P0123 - Ocrelizumab reduces thalamic volume loss and clinical progression in PPMS and RMS independent of baseline NfL and other measures of disease severity (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michelle Gheen, Amit Bar-Or, Gian Thanei, Chris Harp, Corrado Bernasconi, Ulrike Bonati, Anne H. Cross, Sally Fischer, Laura Gaetano, Stephen Hauser, Robert Hendricks, Jens Kuhle, David Leppert, Fabian Model, Harold Koendgen, Xiaoming Jia, Ann Herman

      • Poster Presentation (Video)
    • P0124 - Ocrelizumab treatment in patients with relapsing-remitting multiple sclerosis: a single-center real-world experience (View Presentation)

      Keyword: Clinical Outcome Measures

      Caterina Lapucci, Giacomo Boffa, Maria Cellerino, Giovanni Novi, elvira Sbragia, nicolò Bruschi, Elisabetta Mancuso, francesco Tazza, Alice Laroni, Elisabetta Capello, Antonio Uccelli, Matilde Inglese

      • Poster Presentation (PDF)
    • P0125 - Ocrelizumab treatment induces a sustained blood NfL reduction in patients with PPMS and RMS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michelle Gheen, Amit Bar-Or, Gian Thanei, Chris Harp, Corrado Bernasconi, Ulrike Bonati, Anne Cross, Sally Fischer, Laura Gaetano, Stephen Hauser, Robert Hendricks, Jens Kuhle, David Leppert, Fabian Model, Harold Koendgen, Xiaoming Jia, Ann Herman

      • Poster Presentation (Video)
    • P0126 - Olfactory threshold as a biomarker predicting treatment response in relapsing multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gabriel Bsteh, Harald Hegen, Klaus Berek, Anne Zinganell, Sebastian Wurth, Michael Auer, Franziska Di Pauli, Florian Deisenhammer, Thomas Berger

      • Poster Presentation (PDF)
    • P0127 - Oral therapies for treatment of relapsing-remitting multiple sclerosis in Austria (View Presentation)

      Keyword: Clinical Outcome Measures

      Michael Guger, Christian Enzinger, Fritz Leutmezer, Jörg Kraus, Stefan Kalcher, Erich Kvas, Thomas Berger

      • Poster Presentation (PDF)
    • P0128 - Outcomes in Alemtuzumab-Treated Patients With Thyroid Adverse Events: 6-Year Pooled CARE-MS Data (View Presentation)

      Keyword: Clinical Outcome Measures

      Cameron Duvall, Colin Dayan, Beatriz Lecumberri, Ilaria Muller, Sashiananthan Ganesananthan, Samuel Hunter, Krzysztof Selmaj, Hans Peter Hartung, Eva Havrdova, Christopher Laganke, Tjalf Ziemssen, Bart Van Wijmeersch, Sven Meuth, David Margolin, Salman Afsar, Nadia Daizadeh, Elizabeth Poole, Darren Baker, Peter Senior

      • Poster Presentation (Video)
    • P0129 - Pattern of brain attack occurrence in neuromyelitis optica spectrum disorder: effect of treatment   (View Presentation)

      Keyword: Clinical Outcome Measures

      Min Young Lee, Jae-Won Hyun, Su-Hyun Kim, Ho Jin Kim

      • Poster Presentation (PDF)
    • P0130 - Pediatric MS: different disease course, different impact, different measurement approach needed (View Presentation)

      Keyword: Clinical Outcome Measures

      Nikki Ow, Avi Karp, Joe Ogeil, Marie-Emmanuelle Dilenge, Guillaume Sébire, Nancy Mayo

      • Poster Presentation (PDF)
    • P0131 - Predicting long-term sustained disability progression in multiple sclerosis: application in the CLARITY trial (View Presentation)

      Keyword: Clinical Outcome Measures

      Sifat Sharmin, Francesca Bovis, Maria Pia Sormani, Helmut Butzkueven, Tomas Kalincik

      • Poster Presentation (PDF)
    • P0132 - Prediction of 15-year MS outcomes in BENEFIT trial patients using serum neurofilament light chain concentrations (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Beth Gates, Jens Kuhle, Ludwig Kappos, Mark Freedman, Gilles Edan, Xavier Montalban, Hans Peter Hartung, Frederik Barkhof, Ralf Koelbach, Eva-Maria Wicklein

      • Poster Presentation (PDF)
    • P0133 - Prediction of MS disability status in Japanese claims database using principal component analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Hiromichi Otaka, Kengo Ueda, Kosuke Iwasaki, Tomomi Takeshima, Izumi Kawachi

      • Poster Presentation (PDF)
    • P0134 - Preliminary validation of static posturography as a disability outcome measure in progressive multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Siew Mei Yap, Mark S Etzelmueller, Clodagh O'Keeffe, Maria Gaughan, Richard B Reilly, Christopher McGuigan

      • Poster Presentation (PDF)
    • P0135 - Preventing multiple sclerosis misdiagnosis using the “central vein sign”: A real-world study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Marwa Kaisey, Andrew Solomon, Brooke Guerrero, Brian Renner, Zhaoyang Fan, Natalie Ayala, Michael Luu, Marcio Diniz, Pascal Sati, Nancy Sicotte

      • Poster Presentation (PDF)
    • P0136 - Profiling of small non-coding RNAs across cellular and biofluid compartments in patients with Multiple Sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Galina Zheleznyakova, Eliane Piket, Maria Needhamsen, Michael Hagemann-Jensen, Diana Ekman, Mohsen Khademi, Faiez Al Nimer, Patrick Scicluna, Omid Faridani, Tomas Olsson, Fredrik Piehl, Maja Jagodic

      • Poster Presentation (PDF)
    • P0137 - Prognostic value of NK/T ratios for disease activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Max Mimpen, Anne-Hilde Muris, Linda Rolf, Oliver Gerlach, Jens Kuhle, Raymond Hupperts, Joost Smolders, Jan Damoiseaux

      • Poster Presentation (PDF)
    • P0138 - "Progressive Multifocal Leukoencephalopathy outcomes in Multiple Sclerosis: A Systemic review and Metanalysis "  (View Presentation)

      Keyword: Clinical Outcome Measures

      Shitiz Sriwastava, Shaghayegh Kazemlou, Hamidreza Saber, Samiksha Srivastava, Sarah Peterson, Ronald Gwinn, Saurabh Kataria, Richa Tripathi, Zubeda Sheikh, Sijin Wen, Si Gao, Dhairya Lakhani, Evanthia Bernitsas

      • Poster Presentation (PDF)
    • P0139 - Real World Clinical and Imaging Outcomes in Relapsing MS Patients treated with Alemtuzumab in a US Regional MS Center (View Presentation)

      Keyword: Clinical Outcome Measures

      Duy-Tan Tran, Bhupendra Khatri, Christine Murphy, Lisa Sershon, Omotayo Olapo, Toni Perea, Sara Beals, Lindman Lindman, Elizabeth Poole, Risako Robinson, Avani Patel, Roopali Gandhi, Lobat Hashemi

      • Poster Presentation (PDF)
    • P0140 - Real World Experience of Oral Immune Reconstitution therapy (Cladribine) in the treatment of multiple sclerosis in the United Arab Emirates (View Presentation)

      Keyword: Clinical Outcome Measures

      Mona Thakre, Jihad Inshasi

      • Poster Presentation (PDF)
    • P0141 - Real-world data on the use of Ocrelizumab, among MS patients: B-cell suppression and clinical outcomes. (View Presentation)

      Keyword: Clinical Outcome Measures

      Charmaine Neo, Victoria Singh-Curry, Ashwini Nandoskar, Omar Malik, Rachel Dorsey, Paolo Muraro, Richard Nicholas, Antonio Scalfari

      • Poster Presentation (Video)
    • P0142 - Real-world effectiveness of dimethyl fumarate versus fingolimod using novel outcomes in a heterogeneous patient cohort (View Presentation)

      Keyword: Clinical Outcome Measures

      Carrie Hersh, Yang Lei, Arman Altincatal, Carl De Moor, Richard Rudick, James R. Williams, Catherine Miller, Bernd Kieseier, Irene Koulinska

      • Poster Presentation (Video)
    • P0143 - Real-World Experience in RRMS and SPMS Patients with Higher Disability and Substantial Lymphopenia Switching from Prior DMTs to Teriflunomide (View Presentation)

      Keyword: Clinical Outcome Measures

      Duy-Tan Tran, Regina Berkovich, Nupur Greene, Michael Fernandez, Sam Fadaee, Cuc Quach, Yelena Pyatkevich

      • Poster Presentation (PDF)
    • P0144 - Real-world outcomes in patients with relapsing forms of multiple sclerosis treated with intramuscular interferon beta-1a or peginterferon beta-1a (View Presentation)

      Keyword: Clinical Outcome Measures

      Christina Eavis, Amber Salter, Samantha Lancia, Gary Cutter, Robert Fox, Ruth Ann Marrie, Robin Avila, Megan Vignos

      • Poster Presentation (Video)
    • P0145 - Relation of EDSS to patient-reported outcome measurements in MS: Real-world data from a Swedish nationwide study of fingolimod (IMSE 2) (View Presentation)

      Keyword: Clinical Outcome Measures

      Åsa Leandersson, Stina Kågström, Linda Forsberg, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Peter Sundström, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

      • Poster Presentation (PDF)
    • P0146 - Reliability, concurrent and ecological validity of smartphone-based cognition and walking tests (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ka Hoo Lam, Pim Van Oirschot, Frank Dorssers, Bram Den Teuling, Bernard Uitdehaag, Vincent De Groot, Joep Killestein

      • Poster Presentation (PDF)
    • P0148 - Retinal layer thinning is reflecting disability progression independent of relapse activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gabriel Bsteh, Harald Hegen, Patrick Altmann, Klaus Berek, Sebastian Wurth, Michael Auer, Anne Zinganell, Franziska Di Pauli, Paulus Rommer, Fritz Leutmezer, Florian Deisenhammer, Thomas Berger

      • Poster Presentation (PDF)
    • P0149 - Retinal layer thinning rate as a biomarker predicting treatment response in relapsing multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gabriel Bsteh, Harald Hegen, Klaus Berek, Patrick Altmann, Sebastian Wurth, Michael Auer, Anne Zinganell, Franziska Di Pauli, Paulus Rommer, Fritz Leutmezer, Florian Deisenhammer, Thomas Berger

      • Poster Presentation (PDF)
    • P0150 - REWORD-MS: REal WOrld study to assess the Response to Dimethyl fumarate in patients with Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Maria Francesca Creta, Irene Tramacere, Eugenia Tomas Roldan, Paolo Confalonieri, Valentina Torri Clerici, Carlo Antozzi, Renato Mantegazza, Alessandra Tozzo, Laura Brambilla

      • Poster Presentation (PDF)
    • P0151 - Serum contactin-1 levels as a biomarker of long-term disease progression in natalizumab-treated multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Zoë Van Lierop, Luuk Wieske, Eline Willemse, Iris Dekker, Cyra Leurs, Marleen Koel-Simmelink, Bastiaan Moraal, Frederik Barkhof, Bernard Uitdehaag, Joep Killestein, Charlotte Teunissen

      • Poster Presentation (PDF)
    • P0152 - Serum Neurofilament levels of multiple sclerosis patients before and after treatment with injectable therapies (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      André Huss, Makbule Senel, Ahmed Abdelhak, Benjamin Mayer, Jan Kassubek, Albert Ludolph, Markus Otto, Hayrettin Tumani

      • Poster Presentation (PDF)
    • P0153 - Serum neurofilament light chain and retinal layer thickness measurements are complementary predictors of disease activity in early multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ting-Yi Lin, Viktoriya Vitkova, Ivette Serra, Robyn Cunningham, Susanna Asseyer, Seyedamirhosein Motamedi, Jens Kuhle, Judith Bellmann-Strobl, Klemens Ruprecht, Friedemann Paul, Alexander Brandt, Hanna Zimmermann

      • Poster Presentation (PDF)
    • P0154 - Serum Neurofilament light chain captures and predicts disability progression independent of relapses (PIRA) in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johannes Lorscheider, Pascal Benkert, Özgür Yaldizli, Giulio Disanto, Johanna Oechtering, Sabine Schädelin, Jens Würfel, Andrew Chan, Lutz Achtnichts, Oliver Findling, Tobias Derfuss, Harald Kropshofer, Annette Orleth, Bettina Fischer-Barnicol, Aleksandra Maceski, Dimitri Rey, Sabrina Zadic, Christian Müller, Stefanie Aeschbacher, Emmanuelle Waubant, Jorge Oksenberg, Sven Wellmann, Heinz Wiendl, Ludwig Kappos, Anke Salmen, Robert Hoepner, Patrice Lalive, Renaud Du Pasquier, Caroline Pot, Pietro Maggi, Chiara Zecca, Yvonne Naegelin, Stefanie Müller, Kevin Hrusovsky, Klaus Berger, David Conen, Muhamed Barakovic, Tim Sinnecker, Claudio Gobbi, Cristina Granziera, David Leppert, Jens Kuhle

      • Poster Presentation (PDF)
    • P0155 - Serum neurofilament light chain levels correlate with attack-related disability in neuromyelitis optica spectum disorder (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ian Williams, Orhan Aktas, Hans Peter Hartung, Michael Smith, William Rees, Kazuo Fujihara, Friedemann Paul, Romain Marignier, Jeffrey Bennett, Ho Jin Kim, Brian Weinshenker, Sean Pittock, Dean Wingerchuk, Gary Cutter, Ari Green, Maureen Mealy, Jorn Drappa, Dewei She, Daniel Cimbora, John Ratchford, Eliezer Katz, Bruce Cree

      • Poster Presentation (PDF)
    • P0156 - Serum neurofilament light levels correlate with reduced grey matter volume in advanced multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Arabella Buchmann, Lukas Pirpamer, Daniela Pinter, Maragarete Voortman, Birgit Helmlinger, Alexander Pichler, Gerhard Bachmaier, Stefan Ropele, Christian Enzinger, Michael Khalil

      • Poster Presentation (Video)
    • P0157 - Serum neurofilament light-chain levels and long-term treatment outcomes in relapsing-remitting multiple sclerosis (RRMS) patients in the CombiRx trial (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Christina Eavis, Gary Cutter, Richard Rudick, Carl De Moor, Carol Singh, Elizabeth Fisher, Fred Lublin, Jerry Wolinsky, Henry McFarland, Steven Jacobson, Bernd Kieseier, Maria Naylor

      • Poster Presentation (Video)
    • P0158 - Serum neurofilaments in Secondary Progressive Multiple Sclerosis: analysis from the MS-STAT trial (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Thomas Williams, Katherine Holdsworth, Jennifer Nicholas, Theodora Katsanouli, Henny Wellington, Amanda Heslegrave, Henrik Zetterberg, Chris Frost, Jeremy Chataway

      • Poster Presentation (Video)
    • P0159 - Serum NfL predicts disability progression in MS in a six year longitudinal cohort study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Timo Uphaus, Falk Steffen, Vinzenz Fleischer, Julia Loos, Frauke Zipp, Stefan Bittner

      • Poster Presentation (PDF)
    • P0160 - Serum NfL z-scores derived from a large healthy control group reflect different levels of treatment effect in a real-world setting (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Pascal Benkert, Sabine Schaedelin, Aleksandra Maceski, Giulio Disanto, Johanna Oechtering, Muhamed Barakovic, Annette Orleth, Dimitri Rey, Tim Sinnecker, Özgür Yaldizli, Reza Rahmanzadeh, Sabrina Zadic, Riccardo Galbusera, Ramona-Alexandra Todea, Alessandro Cagol, Lutz Achtnichts, Stefanie Aeschbacher, Andrew Chan, David Conen, Tobias Derfuss, Oliver Findling, Bettina Fischer-Barnicol, Kevin Hrusovsky, Harald Kropshofer, Patrice Lalive, Johanna Lieb, Johannes Lorscheider, Pietro Maggi, Christian Müller, Stefanie Müller, Yvonne Naegelin, Jorge Oksenberg, Caroline Pot, Renaud Du Pasquier, Ernst-Wilhelm Radue, Anke Salmen, Jochen Vehoff, Emmanuelle Waubant, Sven Wellmann, Heinz Wiendl, Jens Wuerfel, Chiara Zecca, Claudio Gobbi, Ludwig Kappos, Klaus Berger, Cristina Granziera, David Leppert, Jens Kuhle

      • Poster Presentation (PDF)
    • P0161 - Short-term evaluation of alemtuzumab to ocrelizumab switch in MS patients with disease activity after alemtuzumab: an Italian multicentric study. (View Presentation)

      Keyword: Clinical Outcome Measures

      Caterina Lapucci, Jessica Frau, Eleonora Cocco, Paola Cavalla, Marco Vercellino, Maria Petracca, Roberta Lanzillo, Paola Grossi, Maria Teresa Ferrò, Clara Guaschino, Mauro Zaffaroni, francesco Tazza, Giovanni Novi, Antonio Uccelli, Matilde Inglese

      • Poster Presentation (PDF)
    • P0162 - Single cell RNA-seq of MS CSF cells reveals a bias toward expanded CD8 T cells (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Grant Feuer, Jonah Vernejoul, Jerry Lin, Saud Sadiq

      • Poster Presentation (Video)
    • P0163 - Smartphone keystroke dynamics are sensitive to changes in disease activity and clinical disability measures in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ka Hoo Lam, James Twose, Hannah McConchie, Giovanni Licitra, Bastiaan Moraal, Frederik Barkhof, Bernard Uitdehaag, Vincent De Groot, Joep Killestein

      • Poster Presentation (Video)
    • P0164 - Smoking is associated with increased plasma neurofilament light levels in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ali Manouchehrinia, Hanna Larsson, Jesse Huang, Lars Alfredsson, Fredrik Piehl, Jens Kuhle, Tomas Olsson, Ingrid Kockum

      • Poster Presentation (PDF)
    • P0165 - Social Matters: Social support is linked to mental health, quality of life, and motor function in multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Anne Kever, Korhan Buyukturkoglu, Claire Riley, Phillip De Jager, Victoria Leavitt

      • Poster Presentation (PDF)
    • P0166 - Sociodemographic features and disability in African-American and Caucasian patients with Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Maria Petracca, Amgad Droby, Mohamed Mounir El Mendili, Swetha Paduri, Nicole Graziano, Natalie Saba, Arielle Falcone, Daniel Kurz, Claire Riley, Jonathan Howard, Sylvia Klineova, Fred Lublin, Matilde Inglese

      • Poster Presentation (PDF)
    • P0167 - Ten-Foot Tandem Walk: Detection of subtle gait changes and future fall risk in MS (View Presentation)

      Keyword: Clinical Outcome Measures

      Rachel Brandstadter, Robin Graney, James Sumowski

      • Poster Presentation (Video)
    • P0168 - Test-retest reliability of the mini-BESTest in people with mild to moderate multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Andreas Wallin, Maire Kierkegaard, Erika Franzén, Sverker Johansson

      • Poster Presentation (PDF)
    • P0169 - The association between spontaneous MxA mRNA level and disease activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Eline Coerver, Laura Van Der Voort, Joep Killestein, E. Strijbis

      • Poster Presentation (PDF)
    • P0170 - The GNDS is suitable for changes in walking performance in progressive multiple sclerosis   (View Presentation)

      Keyword: Clinical Outcome Measures

      Charlotte Van 'T Hullenaar, Nynke Kalkers, Bernard Uitdehaag, Joep Killestein, E. Strijbis

      • Poster Presentation (PDF)
    • P0171 - The gut mycobiome in pediatric multiple sclerosis: establishing a bioinformatics pipeline (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Nelson Mok, Natalie Knox, Douglas L Arnold, Amit Bar-Or, Charles Bernstein, Jessica Forbes, Morag Graham, Janace Hart, Ruth Ann Marrie, Julia O’mahony, E. Ann Yeh, Feng Zhu, Gary Van Domselaar, Brenda Banwell, Emmanuelle Waubant, Helen Tremlett

      • Poster Presentation (Video)
    • P0172 - The prognostic value of lipid-specific IgM oligoclonal bands versus IgM index in patients with a clinical isolated syndrome: a comparative study. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Enric Monreal, Susana Sainz de la Maza, Jose Ignacio Fernandez-Velasco, Paulette Walo Delgado, Mercedes Espiño, Noelia Villarrubia, Ana Gómez López, Jaime Masjuan, Lucienne Costa-Frossard, Luisa María Villar

      • Poster Presentation (PDF)
    • P0173 - The serum levels of Interleukin 17 in patients with neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tarlan Varzandi, Abolfazl Omidifar, Mina Torkamani, Nasim Rezaeimanesh, Razieh Kazemi, Mohammad Ali Sahraian, Abdorreza Naser Moghadasi, Zhila Maghbooli

      • Poster Presentation (PDF)
    • P0174 - TNFα and IL-6 levels in Relapsing-Remitting Multiple Sclerosis Patients on Dimethylfumarate: a Biomarker Study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      William Baek, Song Zhai, Elizabeth Morrison

      • Poster Presentation (PDF)
    • P0175 - Towards optimized monitoring of serum neurofilament light chain in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tomas Uher, Jens Kuhle, Niels Bergsland, Jan Krasensky, Andrija Javor, Barbora Srpová, Christian Barro, Michael Dwyer, Michaela Tyblova, Pascal Benkert, David Leppert, Eva Havrdova, Manuela Vaneckova, Robert Zivadinov, Tomas Kalincik, Dana Horakova

      • Poster Presentation (PDF)
    • P0176 - Treatment and care management, clinical outcomes and mobility impairment in people with or without MS aged ≥ 50 years: observational 6-year analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Nicholas White, Leorah Freeman, Ashlea Lucas, Jia Zhou, Brooke Hayward, Terrie Livingston

      • Poster Presentation (Video)
    • P0177 - Treatment Persistency for Patients in a Phase 2 Long-Term Extension Study of Ponesimod (View Presentation)

      Keyword: Clinical Outcome Measures

      Alexander Keenan, Volker Breu, Hoa Le, Michele Cole, Brian Hennessy

      • Poster Presentation (Video)
    • P0178 - Use of wearable biosensors to collect real-world patient activity data in two randomized phase 2 studies of elezanumab in multiple sclerosis (View Presentation)

      Keyword: Biosensors

      Kim Pfleeger, Adam Ziemann, Bruce Cree

      • Poster Presentation (Video)
    • P0179 - Using NIH Toolbox Standing Balance Test to quantify subtle balance impairment in patients with multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Giacomo Boffa, caterina Lapucci, francesco Tazza, Elisabetta Mancuso, elvira Sbragia, nicolò Bruschi, Maria Cellerino, Matilde Inglese

      • Poster Presentation (PDF)
    • P0180 - Utility of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in tracking treatment response in PPMS patients (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      James Giarraputo, Stephanie Giamberardino, Stephanie Arvai, Christopher Eckstein, Sarah Maichle, L. Newby, Simon Gregory

      • Poster Presentation (PDF)
    • P0182 - Validation of the FeetMe® System versus GAITRite® to Assess Gait Characteristics in Patients with Multiple Sclerosis: Subpopulation analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Anabel Granja Domínguez, Anja Hochsprung, Susana Palao, Cristina Páramo, Aurora Alemán Rodríguez, Carmen Durán, Guillermo Navarro, Ana Venegas, Raúl Romero Sevilla, Maria José Moreno Jiménez, Guillermo Izquierdo

      • Poster Presentation (Video)
    • P0183 - Wearable technologies: where can we focus on next in Multiple Sclerosis? (View Presentation)

      Keyword: Clinical Outcome Measures

      Sarah Alexander, Guy Peryer, Emma Gray, Frederik Barkhof, Jeremy Chataway

      • Poster Presentation (PDF)
    • P0184 - A novel approach to conducting Phase IV studies: The design of the global diroximel fumarate EXPERIENCE study initiative (View Presentation)

      Keyword: Clinical Trials

      Beatrix Bevernage, James Lewin, Jordan Messer, Shivani Kapadia, Irene Koulinska, Sylvia Luca, Miguel Rosales, Carl De Moor, Jason P. Mendoza, Catherine Miller

      • Poster Presentation (Video)
    • P0185 - A phase II randomised controlled trial of a cognitive behavioral therapy intervention for depression in those newly diagnosed with MS (View Presentation)

      Keyword: Clinical Trials

      Litza Kiropoulos, Trevor Kilpatrick, Tomas Kalincik, Leonid Cherulov, Neil Shuey, Tissa Wijeratne

      • Poster Presentation (PDF)
    • P0186 - A Phase 1 study of BIIB091, a Bruton’s tyrosine kinase (BTK) inhibitor, in healthy adult participants: preliminary results (View Presentation)

      Keyword: Clinical Trials

      Matt Scaramozza, Million Arefayene, Xiaomei Peng, Mike Palte, Jeanelle Kam, Alison Graham, Katherine Riester, Alexander Coppell, Eris Bame, Michaël Mingueneau, Brian Hopkins, Shibeshih Belachew, Nathalie Franchimont

      • Poster Presentation (Video)
    • P0187 - A prospective randomized open-label blinded endpoint multicenter non-inferiority study of oral cladribine and rituximab in Multiple Sclerosis (NOR-MS) (View Presentation)

      Keyword: Clinical Trials

      Gro Nygaard, Åslaug Lorentzen, Tone Hognestad, Cecilia Simonsen, Margitta Kampman, Heidi Flemmen, Kristin Wesnes, Alok Bhan, Stein Bjelland, Charlotte Natvig, Kristin Breivik, Kaj Blennow, Henrik Zetterberg, Lars Westlye, Elisabeth Celius, Marte Wendel-Haga, Marissa Leblanc, Johanna Gehin, Helle Stangeland, Tone Berge, Einar Høgestøl, Piotr Sowa, Hanne Harbo

      • Poster Presentation (PDF)
    • P0188 - A Tablet-Based Cognitive Battery to Assess Cognitive Function in People with MS: Sensitivity to Change in A Randomized Controlled Trial (View Presentation)

      Keyword: Clinical Trials

      Wan-Yu Hsu, William Rowles, Joaquin Anguera, Annika Anderson, Adam Gazzaley, Riley Bove

      • Poster Presentation (PDF)
    • P0189 - AQP4-IgG seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Clinical Trials

      Ian Williams, Sean Pittock, Friedemann Paul, Romain Marignier, Ho Jin Kim, Jeffrey Bennett, Brian Weinshenker, Dean Wingerchuk, Ari Green, Kazuo Fujihara, Gary Cutter, Orhan Aktas, Hans Peter Hartung, Jorn Drappa, John Ratchford, Dewei She, Daniel Cimbora, Eliezer Katz, Bruce Cree

      • Poster Presentation (PDF)
    • P0190 - ASPIRE Study: Protocol for a double-blind RCT of aspirin for overheating during exercise in MS (View Presentation)

      Keyword: Clinical Trials

      Victoria Leavitt, Anne Kever, Katherine Nelson, Ines Aguerre, Claire Riley, Phillip De Jager, Amelia Boehme, Rebecca Straus Farber, Seth Levin, Nancy Lee, Joel Stein

      • Poster Presentation (PDF)
    • P0191 - Autologous Stem Cell Transplantation versus Alemtuzumab or Ocrelizumab in Relapsing Remitting Multiple Sclerosis (StarMS) (View Presentation)

      Keyword: Clinical Trials

      Jennifer Petrie, Basil Sharrack, John Snowden, Paolo Muraro

      • Poster Presentation (PDF)
    • P0192 - Benefit-risk of ofatumumab in treatment-naïve early relapsing multiple sclerosis patients (View Presentation)

      Keyword: Clinical Trials

      Jutta Gartner, Stephen Hauser, Amit Bar-Or, Xavier Montalban, Jeffrey Cohen, Anne H. Cross, Kumaran Deiva, Dieter A. Häring, Bingbing Li, Ratnakar Pingili, Krishnan Ramanathan, Wendy Su, Ludwig Kappos

      • Poster Presentation (Video)
    • P0193 - BEST-MS: A standardized and prospective study comparing the efficacy of natalizumab versus fingolimod in active relapsing multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Mikael Cohen, Lydiane Mondot, Florence Bucciarelli, Beatrice Pignolet, David Laplaud, Bruno Brochet, Gilles Defer, Patrick Vermersch, Marc Debouverie, Eric Berger, Pierre Labauge, Jerome De Seze, David Brassat, Christine Lebrun-Frenay

      • Poster Presentation (PDF)
    • P0194 - Cardiac Safety of Ponesimod in Relapsing Multiple Sclerosis in the Randomized, Active-Controlled, Double-Blind, Parallel-Group Phase 3 OPTIMUM Study (View Presentation)

      Keyword: Clinical Trials

      Till Sprenger, Andrea Vaclavkova, Michel Burcklen, Mark Freedman, Robert Fox, Eva Havrdová, Brian Hennessy, Verena Walter, Reinhard Hohlfeld, Fred Lublin, Xavier Montalban, Carlo Pozzilli, Tatiana Scherz, Philippe Linscheid, Magdalena Pirozek-Lawniczek, Hilke Kracker, A Camm, Ludwig Kappos

      • Poster Presentation (PDF)
    • P0195 - Characteristics of Therapeutic Sequences of Patients Enrolled in the PRO-MSACTIVE Study Evaluating Ocrelizumab in Active Relapsing Multiple Sclerosis (View Presentation)

      Keyword: Clinical Trials

      Christine Lebrun-Frenay, Sandra Vukusic, Pierre Labauge, Caroline Bensa, Bertrand Bourre, Eric Manchon, Paul-Henri Depoortere, Marie Lotz, R Niarra, David Laplaud, Isabelle Lawrence

      • Poster Presentation (PDF)
    • P0196 - Cladribine to halt deterioration in people with advanced multiple sclerosis (ChariotMS) (View Presentation)

      Keyword: Clinical Trials

      David Lieberman, Harpreet Mangat, Kimberley Allen-Philbey, David Baker, Frederik Barkhof, Siddharthan Chandran, Christine Chapman, Jeremy Chataway, Helen Ford, Gavin Giovannoni, Jeremy Hobart, Richard Hooper, Tahera Hussain, Neil Walker, David Macmanus, Borislava Mihaylova, Sue Pavitt, Klaus Schmierer

      • Poster Presentation (PDF)
    • P0197 - Clinical relapse rates in relapsing MS patients treated with the BTK inhibitor evobrutinib: results of an open-label extension to a Phase II study (View Presentation)

      Keyword: Clinical Trials

      Xavier Montalban, Douglas L Arnold, Martin Weber, Ivan Staikov, Karolina Piasecka-Stryczynska, Emily Martin, Matthew Mandel, Victor Ona, Fernando Dangond, Jerry Wolinsky

      • Poster Presentation (Video)
    • P0198 - Comparative effectiveness of different DMT strategies in new onset RRMS; First results of the CombatMS trial (View Presentation)

      Keyword: Clinical Trials

      Suvi Virtanen, Fredrik Piehl, Thomas Frisell

      • Poster Presentation (PDF)
    • P0199 - Declining to participate in a randomised controlled trial of a cognitive occupation-based program for people with multiple sclerosis. (View Presentation)

      Keyword: Clinical Trials

      Anusha Moses, Christopher P. Dwyer, Robert Joyce, Dympna Casey, Sinéad M. Hynes

      • Poster Presentation (PDF)
    • P0200 - Diroximel Fumarate in Patients With Relapsing-Remitting Multiple Sclerosis: Interim Safety and Efficacy Results From the Phase 3 EVOLVE-MS-1 Study (View Presentation)

      Keyword: Clinical Trials

      Sibyl Wray, Barry Singer, Jelena Drulovic, Hailu Chen, Jerome Hanna, Jennifer Lyons, Florian Then Bergh, Donald Negroski, Shivani Kapadia

      • Poster Presentation (Video)
    • P0201 - Disability improvement in relapsing-remitting multiple sclerosis patients receiving cladribine tablets, evaluated by expanded disability status scale (View Presentation)

      Keyword: Clinical Trials

      James Plested, Maria Pia Sormani, Gavin Giovannoni, Alessio Signori, Nektaria Alexandri

      • Poster Presentation (Video)
    • P0202 - Durable efficacy of cladribine tablets: cumulative relapse incidence over 5 years in CLARITY and CLARITY Extension (View Presentation)

      Keyword: Clinical Trials

      Esther Dodge, Gavin Giovannoni, Kottil Rammohan, Thomas Leist, Patricia Coyle, Birgit Keller, Dominic Jack, Nektaria Alexandri

      • Poster Presentation (Video)
    • P0203 - Effect of teriflunomide on MRI lesion activity across age groups in patients with relapsing multiple sclerosis from the TEMSO study (View Presentation)

      Keyword: Clinical Trials

      Cameron Duvall, Jiwon Oh, Jens Wuerfel, Bhupendra Khatri, Aaron Miller, Jihad Inshasi, Albert Saiz, Alex Lublin, Elizabeth Poole, Till Sprenger

      • Poster Presentation (Video)
    • P0204 - Effect on disability measures and MSFC in patients with relapsing multiple sclerosis from the phase 3 ponesimod versus teriflunomide optimum study (View Presentation)

      Keyword: Clinical Trials

      shweta Pitre, Robert Fox, Ludwig Kappos, Michel Burcklen, Mark Freedman, Eva Havrdova, Brian Hennessy, Reinhard Hohlfeld, Fred Lublin, Xavier Montalban, Carlo Pozzilli, Tatiana Scherz, Philippe Linscheid, Lisa Ford, Magdalena Pirozek-Lawniczek, Hilke Kracker, Till Sprenger

      • Poster Presentation (Video)
    • P0205 - Effects of Diroximel Fumarate on Brain Volume Change and Disability Progression in Adults With Relapsing-Remitting Multiple Sclerosis From EVOLVE-MS-1 (View Presentation)

      Keyword: Clinical Trials

      Douglas L Arnold, Jiwon Oh, Barry A. Singer, Hailu Chen, Jerome Hanna, Catherine Miller, Robert T. Naismith

      • Poster Presentation (Video)
    • P0206 - Effects of nanocatalysis on CNS bioenergetic markers in patients treated with CNM-Au8: Interim results from two Phase 2 31Phosphorous imaging studies (View Presentation)

      Keyword: Clinical Trials

      Jimin Ren, Austin Rynders, Jacob Evan, Benjamin Greenberg, Richard Dewey, Jr., Karen Ho, Phd, Robert Glanzman, Md, Faan, Michael Hotchkin

      • Poster Presentation (Video)
    • P0207 - Effects of Nurse Practitioner Care compared to Community Neurologist Care on Depression and Anxiety Levels in People with MS: a randomized trial (View Presentation)

      Keyword: Clinical Trials

      Penelope Smyth, Kaitlyn Watson, Karen Turpin, Ross Tsuyuki

      • Poster Presentation (PDF)
    • P0208 - Effects of Wahls Elimination and Swank Dietary Patterns on Multiple Sclerosis Related Fatigue, Quality of Life, Processing Speed and Waking Distance (View Presentation)

      Keyword: Clinical Trials

      Terry Wahls, Warren Darling, Karin Hoth, John Kamholz, Linda Rubenstein, Patrick Ten Eyck, Babita Bisht, Tyler Titcomb, Linda Snetselaar

      • Poster Presentation (Video)
    • P0209 - Efficacy and safety of ofatumumab versus placebo in relapsing multiple sclerosis patients in Japan and Russia: Results from the Phase 2 APOLITOS study (View Presentation)

      Keyword: Clinical Trials

      Arshjyoti Singh, Jun-ichi Kira, Jin Nakahara, Denis V. Sazonov, Takayoshi Kurosawa, Isao Tsumiyama, Roman Willi, Martin Zalesak, Dieter A. Häring, Krishnan Ramanathan, Martin Merschhemke, Ratnakar Pingili, Takahiko Saida

      • Poster Presentation (Video)
    • P0210 - Elezanumab in patients with different disease courses of multiple sclerosis: study design and baseline analysis from two phase 2 studies (View Presentation)

      Keyword: Clinical Trials

      Bruce Cree, Adam Ziemann, Kim Pfleeger, Brittany Schwefel, Annette Wundes, Mark Freedman, Samara Attalla

      • Poster Presentation (Video)